Change the factors. Watch one sample. Each slider acts independently.
The settings describe example habits and exposures. The sample shows illustrative responses. Exercise Regular exercise 0 min/week
About regular exercise Compare weekly minutes of regular physical activity in the example.
Physical activity can support metabolic health and hormone balance. Some studies report better semen measures in active men.
Human association
Exercise does not guarantee better semen or pregnancy. Studies differ, and this example has no prescribed exercise dose.
Weeks to months. This example represents a new sample after development.
Heavy running 0 hours/week
About heavy running Set weekly hours of hard running in a scenario with poor recovery.
Low energy availability, heat, and insufficient recovery can accompany heavy training. These conditions can affect reproductive hormone signals.
Mixed evidence
Running is not inherently harmful. Endurance studies report inconsistent results. The scene shows one possible pathway, without a mileage threshold.
Weeks to months. This example represents a later sample.
Long cycling 0 hours/week
About long cycling Set weekly hours spent in long cycling sessions.
Long sessions can involve local heat and pressure. Some studies report differences in semen measures among cyclists.
Mixed evidence
Studies do not establish a universal cycling threshold. The scene shows a possible adverse example, not an inevitable effect.
Repeated exposure over weeks. This example represents a later sample.
Habits Smoking 0 cigarettes/day
About smoking Set the usual number of cigarettes smoked per day in the example.
Smoke constituents can contribute to oxidative stress and DNA damage. Membrane damage can interfere with active movement.
Human association
A cigarette does not instantly reshape a sperm. The scene does not predict the effect of a cigarette count.
Repeated exposure and sperm development. A new cohort replaces the initial sample.
Alcohol use 0 drinks/week
About alcohol use Set weekly U.S. standard drinks. One standard drink contains 14 grams of pure alcohol.
Chronic heavy alcohol use can disrupt hormone balance and sperm production. Studies also report changes in movement and shape.
Human association
Heavy use differs from moderate consumption. No established dose-response curve converts drinks into the counts in this scene.
Repeated exposure over weeks to months. This scene uses a new sample.
Poor sleep 0 nights/week
About poor sleep Set the number of nights with disrupted sleep in a typical week in the example.
Sleep patterns relate to daily hormone rhythms. Observational studies report associations between disturbed sleep and some semen measures.
Human association
These associations do not prove cause. The model does not prescribe sleep hours or predict damage after a poor night.
Habitual sleep patterns. This example represents a later sample.
Chronic stress 0 days/week
About chronic stress Set the number of days with prolonged stress in a typical week in the example.
Stress-related hormone signals can affect reproductive pathways. Human studies report variable associations with semen measures.
Mixed evidence
Association does not prove cause. A stressful day does not determine sperm quality. This scene shows an uncertain pathway.
Prolonged exposure. This example represents a later sample.
Body Prolonged heat 0 hours/week
About prolonged heat Set weekly hours of extra heat exposure in a repeated exposure scenario.
Increased testicular temperature can disturb sperm production and function. This example changes the later cohort, not the current fluid temperature.
Established mechanism
The model does not measure temperature. Heat sources and individual responses differ. Normal warmth does not imply damage.
Sustained exposure, followed by delayed sample changes.
Fever 0 days
About fever Set how many days a single fever episode lasts in the example.
Fever can disrupt developing sperm. Changes in concentration, movement, and shape can appear after the illness.
Human association
Responses differ with the illness and its timing. This example does not set a recovery date or diagnose an infection.
Delayed effects over subsequent weeks. Recovery also takes time.
Metabolic stress Off
About metabolic stress Choose a modeled level of metabolic stress during sperm development.
Hormone balance, inflammation, and heat can differ with metabolic conditions. Population studies associate obesity with poorer semen measures.
Human association
Body size does not diagnose fertility. Individuals differ, and the scene does not assign a target weight or a fertility score.
Longer-term conditions. This example represents a later sample.
Chemicals External androgens Off
About external androgens Choose a modeled level of exposure to external androgens.
External androgens suppress pituitary signals that support sperm production. A higher blood testosterone level does not guarantee more sperm.
Established mechanism
This scene does not give medication advice or a recovery schedule. Steroid-associated suppression differs from ordinary exercise.
Suppression and recovery develop over months. Individual timing differs.
Certain pesticides Off
About certain pesticides Choose a modeled level of repeated exposure to one example class of chemicals.
Some chemicals can disturb hormone signals or contribute to cellular stress. Effects depend on the substance and exposure.
Human association
Pesticides are not one substance. This scene is not an exposure calculator and does not represent all products.
Substance-specific exposure and sperm development. This example uses a later sample.
Use Explore to follow a swimmer. Click or tap another cell to switch. Drag to stir the sample.
The teaching sample includes common defect examples. Counts do not show their frequency in people.
Red marks illustrated abnormalities. Disconnected red pieces inside the nucleus show schematic DNA fragmentation. The overlay is not ordinary microscopy.
Sliders prepare an illustrative later cohort. Counts do not predict personal fertility.
In this sample
Cells 48
Active motion 32
Forward 23
Slow 10
Nonprogressive 9
Still 16
Alive 45 Two heads Two heads share one connecting region in this example. 4 Small head The head is smaller than the typical model outline. 5 Large head The head is larger than the typical model outline. 1 Tapered head The head narrows toward its tip. 2 Round head The head has a round contour. The drawing does not determine acrosome function. 3 Two tails Two tail branches extend from one cell. 2 Three tails Three tail branches illustrate the multiple-tail category. 1 Bent tail The tail has an angular bend. 2 Coiled tail The tail forms a tight curve or loop. 1 Short tail The tail is shorter than the typical model tail. 2 Absent tail This example has an isolated head without an attached tail. 2 Bent midpiece The connecting region bends away from the head axis. 1 Thick midpiece The midpiece is wider than the typical model outline. 4 Midpiece damage A marker identifies model cellular injury. This trait differs from midpiece shape. 5 DNA fragmentation Separated strand pieces mark model DNA damage. Their number is illustrative. 4 Slow movement This cell has a low active speed in model units. 10 Still, but alive This cell has no active movement and remains alive in the model. 13 Motion without progress This cell moves without a forward path. 9 Traits can overlap. Counts identify cells in this illustrative sample, not causes or diagnoses.
Head · packed DNA Midpiece · mitochondria Tail DNA · enlarged schematic Enlarged schematic. Red marks illustrated abnormalities and DNA fragmentation. The head contains tightly packed DNA. The thin section behind the head is the midpiece. It contains mitochondria. Glycolysis along the tail also supplies energy.
Anatomy and energy: WHO: Laboratory manual for human semen, sixth edition , Separate assessment of head, midpiece, and tail in the WHO manual , Glycolysis and oxidative phosphorylation in sperm movement , Human sperm proportions and longitudinal rolling
All factors start at zero. Change several sliders to explore one combined example.
What acts on this sample? No exposure scenario is active. The sample still contains authored variation in movement, shape, and DNA.
The model explains possible mechanisms. It does not predict fertility, diagnose a condition, or recommend a treatment.
Use this component The package includes a TypeScript core and a React component. The component runs in the browser.
npm install @esmirnov.ai/sperm-lab@0.4.4Read the installation guide
esmirnov.ai